Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | RNR_GSEA_DESEQ2_FC |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | KEGG_LEISHMANIA_INFECTION |
| Enrichment Score (ES) | -0.24753077 |
| Normalized Enrichment Score (NES) | -2.4012299 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0033813373 |
| FWER p-Value | 0.026 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | JAK2 | 1014 | 0.509 | -0.0401 | No | ||
| 2 | HLA-DQA2 | 1217 | 0.435 | -0.0365 | No | ||
| 3 | NOS2 | 1644 | 0.320 | -0.0450 | No | ||
| 4 | IFNG | 1662 | 0.317 | -0.0314 | No | ||
| 5 | TNF | 1751 | 0.302 | -0.0217 | No | ||
| 6 | NFKBIA | 1927 | 0.270 | -0.0166 | No | ||
| 7 | TRAF6 | 2441 | 0.214 | -0.0297 | No | ||
| 8 | ITGA4 | 2791 | 0.186 | -0.0340 | No | ||
| 9 | TLR4 | 4642 | 0.099 | -0.1192 | No | ||
| 10 | MAPK1 | 5144 | 0.085 | -0.1317 | No | ||
| 11 | MAP3K7 | 5198 | 0.083 | -0.1201 | No | ||
| 12 | CR1 | 5660 | 0.071 | -0.1304 | No | ||
| 13 | ELK1 | 6305 | 0.055 | -0.1506 | No | ||
| 14 | IFNGR2 | 6898 | 0.042 | -0.1680 | No | ||
| 15 | TAB2 | 6945 | 0.041 | -0.1560 | No | ||
| 16 | IL10 | 7126 | 0.037 | -0.1512 | No | ||
| 17 | TGFB1 | 7321 | 0.033 | -0.1472 | No | ||
| 18 | MAPK3 | 7950 | 0.020 | -0.1665 | No | ||
| 19 | JAK1 | 8587 | 0.007 | -0.1863 | No | ||
| 20 | ITGB1 | 9615 | -0.013 | -0.2271 | No | ||
| 21 | NFKB1 | 9728 | -0.016 | -0.2187 | No | ||
| 22 | MAPK14 | 9949 | -0.020 | -0.2160 | No | ||
| 23 | PRKCB | 9989 | -0.020 | -0.2036 | No | ||
| 24 | RELA | 10805 | -0.036 | -0.2330 | Yes | ||
| 25 | TGFB2 | 10886 | -0.039 | -0.2229 | Yes | ||
| 26 | ITGAM | 10888 | -0.039 | -0.2084 | Yes | ||
| 27 | TGFB3 | 11101 | -0.044 | -0.2053 | Yes | ||
| 28 | IL4 | 11242 | -0.048 | -0.1984 | Yes | ||
| 29 | JUN | 11703 | -0.058 | -0.2087 | Yes | ||
| 30 | HLA-DMA | 11724 | -0.059 | -0.1953 | Yes | ||
| 31 | HLA-DPA1 | 11815 | -0.061 | -0.1856 | Yes | ||
| 32 | HLA-DMB | 12266 | -0.071 | -0.1954 | Yes | ||
| 33 | FCGR2A | 12338 | -0.073 | -0.1847 | Yes | ||
| 34 | STAT1 | 12866 | -0.088 | -0.1986 | Yes | ||
| 35 | IFNGR1 | 13025 | -0.093 | -0.1926 | Yes | ||
| 36 | TAB1 | 13212 | -0.099 | -0.1882 | Yes | ||
| 37 | NFKBIB | 13217 | -0.099 | -0.1739 | Yes | ||
| 38 | MAPK12 | 13645 | -0.113 | -0.1824 | Yes | ||
| 39 | IRAK4 | 13818 | -0.120 | -0.1772 | Yes | ||
| 40 | ITGB2 | 13945 | -0.125 | -0.1695 | Yes | ||
| 41 | MAPK13 | 14159 | -0.136 | -0.1664 | Yes | ||
| 42 | PTPN6 | 14496 | -0.153 | -0.1700 | Yes | ||
| 43 | NCF2 | 14557 | -0.156 | -0.1588 | Yes | ||
| 44 | TLR2 | 14872 | -0.176 | -0.1612 | Yes | ||
| 45 | HLA-DRA | 14894 | -0.178 | -0.1478 | Yes | ||
| 46 | IL12A | 15174 | -0.199 | -0.1484 | Yes | ||
| 47 | MYD88 | 15234 | -0.203 | -0.1371 | Yes | ||
| 48 | HLA-DPB1 | 15325 | -0.211 | -0.1274 | Yes | ||
| 49 | HLA-DOA | 15422 | -0.220 | -0.1181 | Yes | ||
| 50 | CYBA | 15580 | -0.236 | -0.1121 | Yes | ||
| 51 | MARCKSL1 | 15684 | -0.247 | -0.1031 | Yes | ||
| 52 | IRAK1 | 15778 | -0.260 | -0.0936 | Yes | ||
| 53 | MAPK11 | 15850 | -0.269 | -0.0830 | Yes | ||
| 54 | FCGR3A | 15990 | -0.286 | -0.0760 | Yes | ||
| 55 | C3 | 16057 | -0.294 | -0.0650 | Yes | ||
| 56 | NCF4 | 16204 | -0.318 | -0.0584 | Yes | ||
| 57 | FCGR1A | 16322 | -0.338 | -0.0502 | Yes | ||
| 58 | NCF1 | 16479 | -0.372 | -0.0441 | Yes | ||
| 59 | PTGS2 | 16496 | -0.376 | -0.0305 | Yes | ||
| 60 | FCGR3B | 16570 | -0.393 | -0.0199 | Yes | ||
| 61 | IL12B | 17103 | -0.537 | -0.0341 | Yes | ||
| 62 | HLA-DRB1 | 17183 | -0.571 | -0.0239 | Yes | ||
| 63 | IL1A | 17477 | -0.721 | -0.0252 | Yes | ||
| 64 | HLA-DRB5 | 17494 | -0.732 | -0.0115 | Yes | ||
| 65 | HLA-DOB | 17586 | -0.794 | -0.0019 | Yes | ||
| 66 | FOS | 17601 | -0.807 | 0.0118 | Yes | ||
| 67 | HLA-DQA1 | 17848 | -0.994 | 0.0130 | Yes | ||
| 68 | IL1B | 18055 | -1.190 | 0.0164 | Yes | ||
| 69 | HLA-DQB1 | 18283 | -1.547 | 0.0187 | Yes |
